α-Methylacyl-CoA Racemase from <i>Mycobacterium tuberculosis</i>—Detailed Kinetic and Structural Characterization of the Active Site

α-Methylacyl-CoA Racemase from <i>Mycobacterium tuberculosis</i>—Detailed Kinetic and Structural Characterization of the Active Site

α-Methylacyl-CoA racemase in <i>M. tuberculosis</i> (MCR) has an essential role in fatty acid metabolism and cholesterol utilization, contributing to the bacterium’s survival and persistence. Understanding the enzymatic activity and structural features of MCR provides insights into its p...

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Bibliographic Details
Main Authors: Otsile O. Mojanaga, Timothy J. Woodman, Matthew D. Lloyd, K. Ravi Acharya
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Biomolecules
Subjects:
α-Methylacyl-CoA racemase (AMACR, P504S)
CoA-transferase
colorimetric assay
epimerase
fenoprofen
ibuprofen
Online Access:https://www.mdpi.com/2218-273X/14/3/299

Internet

https://www.mdpi.com/2218-273X/14/3/299

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