VEGF overexpressed mesoangioblasts enhance urethral and vaginal recovery following simulated vaginal birth in rats

Abstract Vaginal birth causes pelvic floor injury which may lead to urinary incontinence. Cell therapy has been proposed to assist in functional recovery. We aim to assess if intra-arterial injection of rat mesoangioblasts (MABs) and stable Vascular Endothelial Growth Factor (VEGF)-expressing MABs,...

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Bibliographic Details
Main Authors: Marina G. M. C. Mori da Cunha, Bernard K. van der Veer, Giorgia Giacomazzi, Katerina Mackova, Laura Cattani, Kian Peng Koh, Greetje Vande Velde, Rik Gijsbers, Maarten Albersen, Maurilio Sampaolesi, Jan Deprest
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35809-x