ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer.

ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer.

The transcription factor, Zinc finger of the cerebellum (ZIC1), plays a crucial role in vertebrate development. Recently, ZIC1 has also been found to participate in the progression of human cancers, including medulloblastomas, endometrial cancers, and mesenchymal neoplasms. However, the function of...

Full description

Bibliographic Details
Main Authors: Lihong Gan, Shujie Chen, Jing Zhong, Xian Wang, Emily K Y Lam, Xin Liu, Jianbin Zhang, Tianhua Zhou, Jun Yu, Jianmin Si, Liangjing Wang, Hongchuan Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21347233/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21347233/?tool=EBI

Similar Items