Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder
Abstract Chronic alcohol exposure increases liver damage such as lipid accumulation and hepatitis, resulting in hepatic cirrhosis. Chronic alcohol intake is known to disturb circadian rhythms in humans and animals. DEC1, a basic helix-loop-helix transcription factor, plays an important role in the c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
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Series: | BMC Molecular and Cell Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12860-023-00497-y |