Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder

Abstract Chronic alcohol exposure increases liver damage such as lipid accumulation and hepatitis, resulting in hepatic cirrhosis. Chronic alcohol intake is known to disturb circadian rhythms in humans and animals. DEC1, a basic helix-loop-helix transcription factor, plays an important role in the c...

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Bibliographic Details
Main Authors: Fuyuki Sato, Ujjal K. Bhawal, Kosuke Oikawa, Yasuteru Muragaki
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Molecular and Cell Biology
Subjects:
Online Access:https://doi.org/10.1186/s12860-023-00497-y