Purification of polyclonal IgG specific for Camelid’s antibodies and their recombinant nanobodies
Camelid’ s heavy-chain antibody (HCAb) consists of only two heavy chains and lacks the two light chains together with the CH1 domain usually found in conventional immunoglobulins. A recombinant single antigen-binding entity, named VHH (or Nanobody®) was generated by reengineering the variable domain...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2016-01-01
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Series: | Open Life Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1515/biol-2016-0001 |