Purification of polyclonal IgG specific for Camelid’s antibodies and their recombinant nanobodies

Camelid’ s heavy-chain antibody (HCAb) consists of only two heavy chains and lacks the two light chains together with the CH1 domain usually found in conventional immunoglobulins. A recombinant single antigen-binding entity, named VHH (or Nanobody®) was generated by reengineering the variable domain...

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Bibliographic Details
Main Authors: Haddad Muhammad, Soukkarieh Chadi, Khalaf Houssam Eddin, Abbady Abdul Qader
Format: Article
Language:English
Published: De Gruyter 2016-01-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2016-0001