Role of immune cells in the removal of deleterious senescent cells

Role of immune cells in the removal of deleterious senescent cells

Abstract Cellular senescence is an essentially irreversible arrest of cell proliferation coupled to a complex senescence-associated secretory phenotype (SASP). The senescence arrest prevents the development of cancer, and the SASP can promote tissue repair. Recent data suggest that the prolonged pre...

Full description

Bibliographic Details
Main Authors: Abhijit Kale, Amit Sharma, Alexandra Stolzing, Pierre-Yves Desprez, Judith Campisi
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Immunity & Ageing
Subjects:
Age-related pathology
Cell-based therapy
Cellular senescence
Immune surveillance
Inflammation
Macrophages
Online Access:http://link.springer.com/article/10.1186/s12979-020-00187-9

Internet

http://link.springer.com/article/10.1186/s12979-020-00187-9

Similar Items