The long multi-epitope peptide vaccine combined with adjuvants improved the therapeutic effects in a glioblastoma mouse model

Emerging data have suggested that single short peptides have limited success as a cancer vaccine; however, extending the short peptides into longer multi-epitope peptides overcame the immune tolerance and induced an immune response. Moreover, the combination of adjuvants such as lenalidomide and ant...

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Bibliographic Details
Main Authors: Thi-Anh-Thuy Tran, Young-Hee Kim, Ga-Eun Kim, Shin Jung, In-Young Kim, Kyung-Sub Moon, Young-Jin Kim, Tae-Kyu Lee, Hyosuk Yun, Je-Jung Lee, Hyun-Ju Lee, Chul Won Lee, Tae-Young Jung
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1007285/full