ZIC3 Controls the Transition from Naive to Primed Pluripotency

Summary: Embryonic stem cells (ESCs) must transition through a series of intermediate cell states before becoming terminally differentiated. Here, we investigated the early events in this transition by determining the changes in the open chromatin landscape as naive mouse ESCs transition to epiblast...

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Bibliographic Details
Main Authors: Shen-Hsi Yang, Munazah Andrabi, Rebecca Biss, Syed Murtuza Baker, Mudassar Iqbal, Andrew D. Sharrocks
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719306370