Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus.

Hepatitis C virus (HCV), a single-stranded positive-sense RNA virus of the Flaviviridae family, infects more than 170 million people worldwide and is the leading cause of liver failure in the United States. A unique feature of HCV is that the viral life cycle depends on cholesterol metabolism in hos...

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Bibliographic Details
Main Author: Jin Ye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.0030108