Discovery and SAR exploration of <it>N</it>-aryl-<it>N</it>-(3-aryl-1,2,4-oxadiazol-5-yl)amines as potential therapeutic agents for prostate cancer
<p>Abstract</p> <p>A new chemical series of antiproliferative compounds was identified <it>via </it>high-throughput screening on DU-145 human prostate carcinoma cell line (hit compound potency - 5.7 μM). Exploration of the two peripheral diversity vectors of the hit mol...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-03-01
|
| Series: | Chemistry Central Journal |
| Online Access: | http://journal.chemistrycentral.com/content/4/1/4 |