Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers

Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers

<p>Abstract</p> <p>Controlling gene expression via small interfering RNA (siRNA) has opened the doors to a plethora of therapeutic possibilities, with many currently in the pipelines of drug development for various ocular diseases. Despite the potential of siRNA technologies, barri...

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Bibliographic Details
Main Authors: Thakur Ajit, Fitzpatrick Scott, Zaman Abeyat, Kugathasan Kapilan, Muirhead Ben, Hortelano Gonzalo, Sheardown Heather
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Biological Engineering
Subjects:
Biomaterials
siRNA
Drug delivery
Endosomal escape
Nanocarriers
Ocular siRNA delivery
RNAi
Online Access:http://www.jbioleng.org/content/6/1/7

Internet

http://www.jbioleng.org/content/6/1/7

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