Molecular Regulation of the RhoGAP GRAF3 and Its Capacity to Limit Blood Pressure In Vivo

Anti-hypertensive therapies are usually prescribed empirically and are often ineffective. Given the prevalence and deleterious outcomes of hypertension (HTN), improved strategies are needed. We reported that the Rho-GAP GRAF3 is selectively expressed in smooth muscle cells (SMC) and controls blood p...

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Bibliographic Details
Main Authors: Rachel A. Dee, Xue Bai, Christopher P. Mack, Joan M. Taylor
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/4/1042