Towards Tissue-Specific Stem Cell Therapy for the Intervertebral Disc: PPARδ Agonist Increases the Yield of Human Nucleus Pulposus Progenitor Cells in Expansion

(1) Background: Low back pain (LBP) is often associated with intervertebral disc degeneration (IVDD). Autochthonous progenitor cells isolated from the center, i.e., the nucleus pulposus, of the IVD (so-called nucleus pulposus progenitor cells (NPPCs)) could be a future cell source for therapy. The N...

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Bibliographic Details
Main Authors: Xingshuo Zhang, Julien Guerrero, Andreas S. Croft, Katharina A.C. Oswald, Christoph E. Albers, Sonja Häckel, Benjamin Gantenbein
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Surgeries
Subjects:
Online Access:https://www.mdpi.com/2673-4095/2/1/8