Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine osteosarcoma

Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine osteosarcoma

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Recent studies demonstrate that immune checkpoint blockade (ICB) increases the chances of the abscopal effect, an anti-tumor effect outside the radiation field in radiation therapy. However, the optimal sequence between radiation and ICB remains unclear. To investigate the impact of sequence of radi...

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Bibliographic Details
Main Authors: Shohei Katsuki, Yutaka Takahashi, Keisuke Tamari, Kazumasa Minami, Wataru Takenaka, Yoriko Ibuki, Junya Yamamoto, Shotaro Tatekawa, Kazuhiko Hayashi, Yuji Seo, Fumiaki Isohashi, Kazuhiko Ogawa, Masahiko Koizumi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273087/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9273087/?tool=EBI

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