Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival

Death mechanisms in status epilepticus-generated neurons and effects of additional seizures on their survival

Status epilepticus (SE) increases neurogenesis in the subgranular zone (SGZ) of the adult dentate gyrus, but many of the newborn cells die, partly through caspase-induced apoptosis. Here we provide immunohistochemical evidence indicating that the caspase-evoked death of the new neurons involves the...

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Bibliographic Details
Main Authors: Christine T Ekdahl, Changlian Zhu, Sara Bonde, Ben A Bahr, Klas Blomgren, Olle Lindvall
Format: Article
Language:English
Published: Elsevier 2003-12-01
Series:Neurobiology of Disease
Subjects:
Neurogenesis
Apoptosis
Seizures
Status epilepticus
Dentate gyrus
Bromodeoxyuridine
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103001682

Internet

http://www.sciencedirect.com/science/article/pii/S0969996103001682

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