Possible integrative actions of leptin and insulin signaling in the hypothalamus targeting energy homeostasis

Obesity has emerged as one of the most burdensome conditions in modern society. In this context, understanding the mechanisms controlling food intake is critical. At present, the adipocyte-derived hormone leptin and the pancreatic β-cell derived hormone insulin are considered the principal anorexige...

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Bibliographic Details
Main Authors: Mina Thon, Toru Hosoi, Koichiro Ozawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00138/full