Gastric Th17 Cells Specific for H+/K+-ATPase and Serum IL-17 Signature in Gastric Autoimmunity

Gastric Th17 Cells Specific for H+/K+-ATPase and Serum IL-17 Signature in Gastric Autoimmunity

Human gastric autoimmunity [autoimmune gastritis (AIG)] is characterized by inflammation of the gastric mucosa and parietal cell loss. The gastric parietal cell proton pump H+/K+-adenosine triphosphatase (H+/K+-ATPase) is the major autoantigen in AIG. Our work aimed to investigate the gastric H+/K+-...

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Bibliographic Details
Main Authors: Chiara Della Bella, Antonio Antico, Maria Piera Panozzo, Nagaja Capitani, Luisa Petrone, Marisa Benagiano, Sofia D’Elios, Clotilde Sparano, Annalisa Azzurri, Sara Pratesi, Fabio Cianchi, Diana Ortiz-Princz, Mathijs Bergman, Nicola Bizzaro, Mario Milco D’Elios
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
T cells
Th17
gastric autoantigen
gastric autoimmunity
gastric cancer
H+/K+-ATPase
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.952674/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.952674/full

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