SK4 channels modulate Ca2+ signalling and cell cycle progression in murine breast cancer

SK4 channels modulate Ca2+ signalling and cell cycle progression in murine breast cancer

Oncogenic signalling via Ca2+‐activated K+ channels of intermediate conductance (SK4, also known as KCa3.1 or IK) has been implicated in different cancer entities including breast cancer. Yet, the role of endogenous SK4 channels for tumorigenesis is unclear. Herein, we generated SK4‐negative tumours...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Friederike A. Steudel, Corinna J. Mohr, Benjamin Stegen, Hoang Y. Nguyen, Andrea Barnert, Marc Steinle, Sandra Beer‐Hammer, Pierre Koch, Wing‐Yee Lo, Werner Schroth, Reiner Hoppe, Hiltrud Brauch, Peter Ruth, Stephan M. Huber, Robert Lukowski
स्वरूप: लेख
भाषा:English
प्रकाशित: Wiley 2017-09-01
श्रृंखला:Molecular Oncology
विषय:
breast cancer
Ca2+‐activated K+ channels of intermediate conductance (SK4, KCa3.1, IK, KCNN4)
epidermal growth factor receptor 2 (Her2/cNeu)
mouse mammary tumour virus (MMTV)
polyoma virus middle T‐antigen (PyMT)
ऑनलाइन पहुंच:https://doi.org/10.1002/1878-0261.12087

इंटरनेट

https://doi.org/10.1002/1878-0261.12087

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