Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan women.

A reservoir of HIV-infected cells that persists despite suppressive antiretroviral therapy (ART) is the source of viral rebound upon ART cessation and the major barrier to a cure. Understanding reservoir seeding dynamics will help identify the best timing for HIV cure strategies. Here we characteriz...

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Bibliographic Details
Main Authors: Mark D Pankau, Daniel B Reeves, Elias Harkins, Keshet Ronen, Walter Jaoko, Kishor Mandaliya, Susan M Graham, R Scott McClelland, Frederick A Matsen Iv, Joshua T Schiffer, Julie Overbaugh, Dara A Lehman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008286