Hyperactivation of p21-Activated Kinases in Human Cancer and Therapeutic Sensitivity

Hyperactivation of p21-Activated Kinases in Human Cancer and Therapeutic Sensitivity

Over the last three decades, p21-activated kinases (PAKs) have emerged as prominent intracellular nodular signaling molecules in cancer cells with a spectrum of cancer-promoting functions ranging from cell survival to anchorage-independent growth to cellular invasiveness. As PAK family members are w...

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Bibliographic Details
Main Authors: Deivendran Sankaran, Revikumar Amjesh, Aswathy Mary Paul, Bijesh George, Rajat Kala, Sunil Saini, Rakesh Kumar
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
PAKs
cancer
metastasis
therapeutic sensitivity
combination therapy
clinical trials
Online Access:https://www.mdpi.com/2227-9059/11/2/462

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https://www.mdpi.com/2227-9059/11/2/462

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