Genetic variations in key microRNA processing genes and risk of head and neck cancer: a case-control study in Chinese population.

MicroRNAs (miRNAs) have been reported to play a key role in oncogenesis. Genetic variations in miRNA processing genes and miRNA binding sites may affect the biogenesis of miRNA and the miRNA-mRNA interactions, hence promoting tumorigenesis. In the present study, we hypothesized that potentially func...

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Bibliographic Details
Main Authors: Hongxia Ma, Hua Yuan, Zhiyao Yuan, Chenjie Yu, Ruixia Wang, Yue Jiang, Zhibin Hu, Hongbing Shen, Ning Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3469541?pdf=render