Preeclampsia is Associated With Reduced ISG15 Levels Impairing Extravillous Trophoblast Invasion

Preeclampsia is Associated With Reduced ISG15 Levels Impairing Extravillous Trophoblast Invasion

Among several interleukin (IL)-6 family members, only IL-6 and IL-11 require a gp130 protein homodimer for intracellular signaling due to lack of intracellular signaling domain in the IL-6 receptor (IL-6R) and IL-11R. We previously reported enhanced decidual IL-6 and IL-11 levels at the maternal-fet...

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Bibliographic Details
Main Authors: Asli Ozmen, Ozlem Guzeloglu-Kayisli, Selcuk Tabak, Xiaofang Guo, Nihan Semerci, Chinedu Nwabuobi, Kellie Larsen, Ali Wells, Asli Uyar, Sefa Arlier, Ishani Wickramage, Hasan Alhasan, Hana Totary-Jain, Frederick Schatz, Anthony O. Odibo, Charles J. Lockwood, Umit A. Kayisli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ISG15
IL6
IL11
preeclampsia
extravillous trophoblast
differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.898088/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.898088/full

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