Energy Scarcity Promotes a Brain-wide Sleep State Modulated by Insulin Signaling in C. elegans

Energy Scarcity Promotes a Brain-wide Sleep State Modulated by Insulin Signaling in C. elegans

Neural information processing entails a high energetic cost, but its maintenance is crucial for animal survival. However, the brain’s energy conservation strategies are incompletely understood. Employing functional brain-wide imaging and quantitative behavioral assays, we describe a neuronal strateg...

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Bibliographic Details
Main Authors: Susanne Skora, Fanny Mende, Manuel Zimmer
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cell Reports
Subjects:
energy homeostasis
starvation
insulin signaling
daf-2
whole-brain imaging
behavior
sleep
arousal
neuronal population dynamics
Caenorhabditis elegans
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717319289

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http://www.sciencedirect.com/science/article/pii/S2211124717319289

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