Regulation of glucose uptake in lymphoma cell lines by c-MYC- and PI3K-dependent signaling pathways and impact of glycolytic pathways on cell viability

Regulation of glucose uptake in lymphoma cell lines by c-MYC- and PI3K-dependent signaling pathways and impact of glycolytic pathways on cell viability

Abstract Background Changes in glucose and energy metabolism contribute to the altered phenotype of cancer cells and are the basis for positron emission tomography with 18F-fluoro-2-deoxy-d-glucose (FDG) to visualize tumors in vivo. The molecular background of the enhanced glucose uptake and its reg...

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Bibliographic Details
Main Authors: Martina Broecker-Preuss, Nina Becher-Boveleth, Andreas Bockisch, Ulrich Dührsen, Stefan Müller
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Journal of Translational Medicine
Subjects:
Warburg effect
Glucose metabolism
Lymphoma
18F-fluoro-2-deoxy-d-glucose
2-deoxy-d-glucose
Online Access:http://link.springer.com/article/10.1186/s12967-017-1258-9

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http://link.springer.com/article/10.1186/s12967-017-1258-9

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