Genetic dissection of regulation by a repressing and novel activating corrinoid riboswitch enables engineering of synthetic riboswitches
ABSTRACT The ability to sense and respond to intracellular metabolite levels enables cells to adapt to environmental conditions. Many prokaryotes use riboswitches—structured RNA elements usually located in the 5′ untranslated region of mRNAs—to sense intracellular metabolites and respond by modulati...
Main Authors: | Rebecca R. Procknow, Kristopher J. Kennedy, Maxwell Kluba, Lesley J. Rodriguez, Michiko E. Taga |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-10-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.01588-23 |
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