Chitosan/Alginate Nanoparticles for the Enhanced Oral Antithrombotic Activity of Clam Heparinoid from the Clam <i>Coelomactra antiquata</i>

Chitosan/Alginate Nanoparticles for the Enhanced Oral Antithrombotic Activity of Clam Heparinoid from the Clam <i>Coelomactra antiquata</i>

Chitosan/alginate nanoparticles (DG1-NPs and DG1/Cur-NPs) aiming to enhance the oral antithrombotic activity of clam heparinoid DG1 were prepared by ionotropic pre-gelation. The influence of parameters, such as the concentration of sodium alginate (SA), chitosan (CTS), CaCl<sub>2</sub>,...

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Bibliographic Details
Main Authors: Guan-Lan Chen, Hong-Ying Cai, Jian-Ping Chen, Rui Li, Sai-Yi Zhong, Xue-Jing Jia, Xiao-Fei Liu, Bing-Bing Song
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Marine Drugs
Subjects:
clam heparinoid
oral administration
antithrombotic
chitosan/alginate nanoparticles
Online Access:https://www.mdpi.com/1660-3397/20/2/136

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https://www.mdpi.com/1660-3397/20/2/136

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