High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
Pore-forming proteins (PFPs) represent a functionally important protein family, that are found in organisms from viruses to humans. As a major branch of PFPs, bacteria pore-forming toxins (PFTs) permeabilize membranes and usually cause the death of target cells. E. coli hemolysin ClyA is the first m...
Main Authors: | Wei Peng, Marcela de Souza Santos, Yang Li, Diana R Tomchick, Kim Orth |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0213423 |
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