Loss of a Functional Mitochondrial Pyruvate Carrier in <i>Komagataella phaffii</i> Does Not Improve Lactic Acid Production from Glycerol in Aerobic Cultivation

Loss of a Functional Mitochondrial Pyruvate Carrier in <i>Komagataella phaffii</i> Does Not Improve Lactic Acid Production from Glycerol in Aerobic Cultivation

Cytosolic pyruvate is an essential metabolite in lactic acid production during microbial fermentation. However, under aerobiosis, pyruvate is transported to the mitochondrial matrix by the mitochondrial pyruvate carrier (MPC) and oxidized in cell respiration. Previous reports using <i>Saccharo...

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Bibliographic Details
Main Authors: Ana Caroline de Oliveira Junqueira, Nadielle Tamires Moreira Melo, Nádia Skorupa Parachin, Hugo Costa Paes
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Microorganisms
Subjects:
mitochondrial pyruvate carrier 1
bacterial hemoglobin
L-leucine
qPCR
PLA
Online Access:https://www.mdpi.com/2076-2607/11/2/483

Internet

https://www.mdpi.com/2076-2607/11/2/483

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