Elevated IFNA1 and suppressed IL12p40 associated with persistent hyperinflammation in COVID-19 pneumonia

Elevated IFNA1 and suppressed IL12p40 associated with persistent hyperinflammation in COVID-19 pneumonia

IntroductionDespite of massive endeavors to characterize inflammation in COVID-19 patients, the core network of inflammatory mediators responsible for severe pneumonia stillremain remains elusive. MethodsHere, we performed quantitative and kinetic analysis of 191 inflammatory factors in 955 plasma s...

Full description

Bibliographic Details
Main Authors: Kyeongseok Jeon, Yuri Kim, Shin Kwang Kang, Uni Park, Jayoun Kim, Nanhee Park, Jaemoon Koh, Man-Shik Shim, Minsoo Kim, Youn Ju Rhee, Hyeongseok Jeong, Siyoung Lee, Donghyun Park, Jinyoung Lim, Hyunsu Kim, Na-Young Ha, Hye-Yeong Jo, Sang Cheol Kim, Ju-Hee Lee, Jiwon Shon, Hoon Kim, Yoon Kyung Jeon, Youn-Soo Choi, Hye Young Kim, Won-Woo Lee, Murim Choi, Hyun-Young Park, Woong-Yang Park, Yeon-Sook Kim, Nam-Hyuk Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
pneumonia
inflammation
IFNa
IL-12p40
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1101808/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1101808/full

Similar Items