Concomitant Kinase-Dead BRAF and Oncogenic KRAS Lead to an Aggressive Biologic Behavior and Tumor Lysis Syndrome: A Case Report

Concomitant Kinase-Dead BRAF and Oncogenic KRAS Lead to an Aggressive Biologic Behavior and Tumor Lysis Syndrome: A Case Report

Tumor lysis syndrome (TLS) is a life-threatening oncological emergency rarely seen in solid tumors and is a complication of cancer therapy for rapidly proliferating tumors with devastating outcomes. BRAF and KRAS are two key oncogenes in the MAPK signaling pathway that are routinely examined for mut...

Full description

Bibliographic Details
Main Authors: Roy Holland, Offir Ben-Ishay, Irit Ben-Aharon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
tumor lysis syndrome
case report
concomitant BRAF and KRAS mutations
duodenal mucinous adenocarcinoma
NGS - next generation sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.885814/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.885814/full

Similar Items