Combination of [<sup>177</sup>Lu]Lu-DOTA-TATE Targeted Radionuclide Therapy and Photothermal Therapy as a Promising Approach for Cancer Treatment: In Vivo Studies in a Human Xenograft Mouse Model

Combination of [<sup>177</sup>Lu]Lu-DOTA-TATE Targeted Radionuclide Therapy and Photothermal Therapy as a Promising Approach for Cancer Treatment: In Vivo Studies in a Human Xenograft Mouse Model

Peptide receptor radionuclide therapy (PRRT) relies on α- and β-emitting radionuclides bound to a peptide that commonly targets somatostatin receptors (SSTRs) for the localized killing of tumors through ionizing radiation. A Lutetium-177 (<sup>177</sup>Lu)-based probe linked to the somat...

Full description

Bibliographic Details
Main Authors: Marina Simón, Jesper Tranekjær Jørgensen, Harshvardhan A. Khare, Camilla Christensen, Carsten Haagen Nielsen, Andreas Kjaer
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
photothermal therapy (PTT)
nanoshells (NS)
peptide receptor radionuclide therapy (PRRT)
[<sup>177</sup>Lu]Lu-DOTA-TATE
somatostatin receptor (SSTR)
cancer
Online Access:https://www.mdpi.com/1999-4923/14/6/1284

Internet

https://www.mdpi.com/1999-4923/14/6/1284

Similar Items