Evaluation of prothrombotic risk of two PROC hotspot mutations (Arg189Trp and Lys193del) in Chinese population: a retrospective study

Evaluation of prothrombotic risk of two PROC hotspot mutations (Arg189Trp and Lys193del) in Chinese population: a retrospective study

Abstract Background R189W and K193del of protein C (PC) were hotspot mutations in Chinese population with venous thromboembolism (VTE), but almost two-thirds of patients with above mutations coexisting with other genetically or aquiredly prothrombotic risk factors. The aim of this study is to clarif...

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Bibliographic Details
Main Authors: Lei Li, Jian Li, Xi Wu, Wenman Wu, Qiulan Ding, Baohua Qian, Xuefeng Wang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Thrombosis Journal
Subjects:
Protein C deficiency
Hotspot mutation
Venous thromboembolism
Risk factors
Online Access:https://doi.org/10.1186/s12959-023-00548-6

Internet

https://doi.org/10.1186/s12959-023-00548-6

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