<i>N</i>-Acetylcysteine Inhibits Platelet Function through the Regeneration of the Non-Oxidative Form of Albumin

<i>N</i>-Acetylcysteine Inhibits Platelet Function through the Regeneration of the Non-Oxidative Form of Albumin

<i>N</i>-acetylcysteine (NAC) is able to break down protein disulfides, generating free thiols. This mechanism occurs on mixed disulfides of albumin (HSA) to form mercaptoalbumin (HMA), the main antioxidant species in the plasma. Circulating HSA exists in two main forms: the reduced form...

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Bibliographic Details
Main Authors: Sonia Eligini, Benedetta Porro, Giancarlo Aldini, Susanna Colli, Cristina Banfi
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Antioxidants
Subjects:
<i>N</i>-acetylcysteine
albumin
platelets
aggregation
arachidonic acid metabolites
adhesion
Online Access:https://www.mdpi.com/2076-3921/11/3/445

Internet

https://www.mdpi.com/2076-3921/11/3/445

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