Qinhuo Shanggan oral solution resolves acute lung injury by down-regulating TLR4/NF-κB signaling cascade and inhibiting NLRP3 inflammasome activation

Qinhuo Shanggan oral solution resolves acute lung injury by down-regulating TLR4/NF-κB signaling cascade and inhibiting NLRP3 inflammasome activation

Acute lung injury (ALI) is a common condition, particularly in the COVID-19 pandemic, which is distinguished by sudden onset of respiratory insufficiency with tachypnea, oxygen-refractory cyanosis, reduced lung compliance and diffuse infiltration of pulmonary alveoli. It is well-established that inc...

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Bibliographic Details
Main Authors: Shun Tang, Yuanjing Liang, Minmin Wang, Jiarong Lei, Yuhui Peng, Qiu Tao, Tianqi Ming, Wenyu Yang, Chuantao Zhang, Jinlin Guo, Haibo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
acute lung injury (ALI)
TLR4 (toll-like receptor 4)
NF- kappa B
NLRP3
cytokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285550/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1285550/full

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