Gene Fusions Associated with Recurrent Amplicons Represent a Class of Passenger Aberrations in Breast Cancer

Gene Fusions Associated with Recurrent Amplicons Represent a Class of Passenger Aberrations in Breast Cancer

Application of high-throughput transcriptome sequencing has spurred highly sensitive detection and discovery of gene fusions in cancer, but distinguishing potentially oncogenic fusions from random, “passenger” aberrations has proven challenging. Here we examine a distinctive group of gene fusions th...

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Bibliographic Details
Main Authors: Shanker Kalyana-Sundaram, Sunita Shankar, Scott DeRoo, Matthew K. Iyer, Nallasivam Palanisamy, Arul M. Chinnaiyan, Chandan Kumar-Sinha
Format: Article
Language:English
Published: Elsevier 2012-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800042

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http://www.sciencedirect.com/science/article/pii/S1476558612800042

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