Inhibition of furin-like enzymatic activities and SARS-CoV-2 infection by osthole and phenolic compounds with aryl side chains

Inhibition of furin-like enzymatic activities and SARS-CoV-2 infection by osthole and phenolic compounds with aryl side chains

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread as a pandemic and caused damage to people’s lives and countries’ economies. The spike (S) protein of SARS-CoV-2 contains a cleavage motif, Arg-X-X-Arg, for furin and furin-like enzymes...

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Bibliographic Details
Main Authors: Yuka Kiba, Takashi Tanikawa, Tsuyoshi Hayashi, Hitoshi Kamauchi, Taishi Seki, Ryuichiro Suzuki, Masashi Kitamura
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Furin
SARS-CoV-2
Osthole
Coumarin
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223017389

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http://www.sciencedirect.com/science/article/pii/S0753332223017389

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