Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes

Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes

Functionalization of experimental HIV-1 virus-like particle vaccines with heterologous T helper epitopes (T helper VLPs) can modulate the humoral immune response via intrastructural help (ISH). Current advances in the conjugation of native-like HIV-1 envelope trimers (Env) onto liposomes and encapsu...

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Bibliographic Details
Main Authors: Dominik Damm, Ehsan Suleiman, Hannah Theobald, Jannik T. Wagner, Mirjam Batzoni, Bianca Ahlfeld (née Kohlhauser), Bernd Walkenfort, Jens-Christian Albrecht, Jidnyasa Ingale, Lifei Yang, Mike Hasenberg, Richard T. Wyatt, Karola Vorauer-Uhl, Klaus Überla, Vladimir Temchura
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
T helper liposomes
Env trimer
coupling mechanism
peptide encapsulation
intrastructural help
HIV
Online Access:https://www.mdpi.com/1999-4923/14/7/1385

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https://www.mdpi.com/1999-4923/14/7/1385

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