Profiling the heterogeneity of colorectal cancer consensus molecular subtypes using spatial transcriptomics

Profiling the heterogeneity of colorectal cancer consensus molecular subtypes using spatial transcriptomics

Abstract The consensus molecular subtypes (CMS) of colorectal cancer (CRC) is the most widely-used gene expression-based classification and has contributed to a better understanding of disease heterogeneity and prognosis. Nevertheless, CMS intratumoral heterogeneity restricts its clinical applicatio...

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Main Authors: Alberto Valdeolivas, Bettina Amberg, Nicolas Giroud, Marion Richardson, Eric J. C. Gálvez, Solveig Badillo, Alice Julien-Laferrière, Demeter Túrós, Lena Voith von Voithenberg, Isabelle Wells, Benedek Pesti, Amy A. Lo, Emilio Yángüez, Meghna Das Thakur, Michael Bscheider, Marc Sultan, Nadine Kumpesa, Björn Jacobsen, Tobias Bergauer, Julio Saez-Rodriguez, Sven Rottenberg, Petra C. Schwalie, Kerstin Hahn
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00488-4

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https://doi.org/10.1038/s41698-023-00488-4

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