Local autoimmune encephalomyelitis model in a rat brain with precise control over lesion placement

Development of a novel, animal model for multiple sclerosis (MS) with reproducible and predictable lesion placement would enhance the discovery of effective treatments. Therefore, we would like to combine the advantages of the demyelination model with experimental autoimmune encephalomyelitis (EAE)...

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Bibliographic Details
Main Authors: Lukasz Kalkowski, Dominika Golubczyk, Joanna Kwiatkowska, Malgorzata Domzalska, Piotr Walczak, Izabela Malysz-Cymborska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782401/?tool=EBI