Characterization of pancreatic islets in two selectively bred mouse lines with different susceptibilities to high-fat diet-induced glucose intolerance.

Hereditary predisposition to diet-induced type 2 diabetes has not yet been fully elucidated. We recently established 2 mouse lines with different susceptibilities (resistant and prone) to high-fat diet (HFD)-induced glucose intolerance by selective breeding (designated selectively bred diet-induced...

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Bibliographic Details
Main Authors: Mototsugu Nagao, Akira Asai, Wataru Inaba, Momoyo Kawahara, Yuki Shuto, Shunsuke Kobayashi, Daisuke Sanoyama, Hitoshi Sugihara, Soroku Yagihashi, Shinichi Oikawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3890274?pdf=render