Synthesis and Cytotoxic Activity Evaluation of New Cu(I) Complexes of Bis(pyrazol-1-yl) Acetate Ligands Functionalized with an NMDA Receptor Antagonist

Synthesis and Cytotoxic Activity Evaluation of New Cu(I) Complexes of Bis(pyrazol-1-yl) Acetate Ligands Functionalized with an NMDA Receptor Antagonist

In the present article, copper(I) complexes of bis(pyrazol-1-yl) carboxylic acid (LH), bis(3,5-dimethylpyrazol-1-yl) carboxylic acid (L<sup>2</sup>H), and bis(pyrazol-1-yl) acetates conjugated with an <i>N</i>-methyl-<span style="font-variant: small-caps;">d&l...

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Bibliographic Details
Main Authors: Maura Pellei, Luca Bagnarelli, Lorenzo Luciani, Fabio Del Bello, Gianfabio Giorgioni, Alessandro Piergentili, Wilma Quaglia, Michele De Franco, Valentina Gandin, Cristina Marzano, Carlo Santini
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
copper complexes
antitumor activity
metal-based drugs
bifunctionalized ligands
NMDA receptor ligand
Online Access:https://www.mdpi.com/1422-0067/21/7/2616

Internet

https://www.mdpi.com/1422-0067/21/7/2616

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