Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration

Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration

The development of drug resistance in tumors is a major obstacle to effective cancer chemotherapy and represents one of the most significant complications to improving long-term patient outcomes. Despite early positive responsiveness to platinum-based chemotherapy, the majority of lung cancer patien...

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Bibliographic Details
Main Authors: Medhi Wangpaichitr, George Theodoropoulos, Dan J. M. Nguyen, Chunjing Wu, Sydney A. Spector, Lynn G. Feun, Niramol Savaraj
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
cisplatin resistance
metabolism
oxidative metabolism
reactive oxygen species
Online Access:https://www.mdpi.com/1422-0067/22/14/7379

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https://www.mdpi.com/1422-0067/22/14/7379

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