Contributing Factors for Mutagenic DNA Lesion Bypass by DNA Polymerase Eta (polη)
The integrity of DNA replication is under constant threat from various exogenous and endogenous factors along with some epigenetic factors. When there is damage to the genome, cells respond to the damage in two major ways, DNA damage repair and DNA damage tolerance. One of the major mechanisms for D...
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Format: | Article |
Language: | English |
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MDPI AG
2022-09-01
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Series: | DNA |
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Online Access: | https://www.mdpi.com/2673-8856/2/4/15 |