Surface Display of porcine circovirus type 2 antigen protein cap on the spores of bacillus subtilis 168: An effective mucosal vaccine candidate

Surface Display of porcine circovirus type 2 antigen protein cap on the spores of bacillus subtilis 168: An effective mucosal vaccine candidate

The oral mucosal vaccine has great potential in preventing a series of diseases caused by porcine circovirus type 2 (PCV2) infection. This study constructed a recombinant Bacillus subtilis RB with PCV2 Capsid protein (Cap) on its spore surface and cotB as a fusion partner. The immune properties of t...

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Bibliographic Details
Main Authors: Weijie Li, Jianzhen Li, Xixi Dai, Minggang Liu, Abdul Khalique, Zhenghua Wang, Yan Zeng, Dongmei Zhang, Xueqin Ni, Dong Zeng, Bo Jing, Kangcheng Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Porcine circovirus type 2(PCV2)
capsid protein
Bacillus subtilis
spore surface display
oral mucosal vaccine
mucosal immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1007202/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1007202/full

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