Synonymous Variants of Uncertain Silence

Synonymous Variants of Uncertain Silence

Synonymous variants, traditionally regarded as silent mutations due to their lack of impact on protein sequence, structure and function, have been the subject of increasing scrutiny. This commentary explores the emerging evidence challenging the notion of synonymous variants as functionally inert. A...

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Bibliographic Details
Main Authors: Christopher J. Giacoletto, Jerome I. Rotter, Wayne W. Grody, Martin R. Schiller
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
synonymous variant
silent variant
sequence
variant interpretation
Online Access:https://www.mdpi.com/1422-0067/24/13/10556

Internet

https://www.mdpi.com/1422-0067/24/13/10556

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