Selective somatostatin receptor 5 inhibition improves hepatic insulin sensitivity

Selective somatostatin receptor 5 inhibition improves hepatic insulin sensitivity

Abstract Diabetes is a metabolic disorder with an increasing global prevalence. Somatostatin (SST), a peptide hormone, regulates hormone secretion via five SST receptor (SSTR) subtypes (SSTR1–5) in a tissue‐specific manner. As SSTR5 is expressed in pancreatic β‐cells and intestinal L‐cells, studies...

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Bibliographic Details
Main Authors: Yumiko Okano Tamura, Jun Sugama, Shin‐ichi Abe, Yuji Shimizu, Hideki Hirose, Masanori Watanabe
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Pharmacology Research & Perspectives
Subjects:
hepatic insulin resistance
somatostatin
SSTR5
type 2 diabetes
Online Access:https://doi.org/10.1002/prp2.1043

Internet

https://doi.org/10.1002/prp2.1043

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