PriPath: identifying dysregulated pathways from differential gene expression via grouping, scoring, and modeling with an embedded feature selection approach

Abstract Background Cell homeostasis relies on the concerted actions of genes, and dysregulated genes can lead to diseases. In living organisms, genes or their products do not act alone but within networks. Subsets of these networks can be viewed as modules that provide specific functionality to an...

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Bibliographic Details
Main Authors: Malik Yousef, Fatma Ozdemir, Amhar Jaber, Jens Allmer, Burcu Bakir-Gungor
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-023-05187-2