Molecular docking, 2D-QSAR and ADMET studies of 4-sulfonyl-2-pyridone heterocycle as a potential glucokinase activator

Glucokinase is one of the key enzymes for the management of diabetes mellitus. Although the literature has reported numerous molecules for lowering the blood glucose level, still no single moiety has been developed for the management of diabetes mellitus. So, there is an urgent need for the developm...

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Bibliographic Details
Main Authors: Prateek Sharma, Aman Thakur, Anju Goyal, Ajmer Singh Grewal
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623003442