Molecular docking, 2D-QSAR and ADMET studies of 4-sulfonyl-2-pyridone heterocycle as a potential glucokinase activator
Glucokinase is one of the key enzymes for the management of diabetes mellitus. Although the literature has reported numerous molecules for lowering the blood glucose level, still no single moiety has been developed for the management of diabetes mellitus. So, there is an urgent need for the developm...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
|
Series: | Results in Chemistry |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715623003442 |