Serum circulating sirtuin 6 as a novel predictor of mortality after acute ischemic stroke

Serum circulating sirtuin 6 as a novel predictor of mortality after acute ischemic stroke

Abstract In a murine model of acute ischemic stroke, SIRT6 knockdown resulted in larger cerebral infarct size, worse neurological outcome, and higher mortality, indicating a possible neuro-protective role of SIRT6. In this study, we aimed at evaluating the prognostic value of serum SIRT6 levels in p...

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Bibliographic Details
Main Authors: Luca Liberale, Stefano Ministrini, Markus Arnold, Yustina M. Puspitasari, Thomas Pokorny, Georgia Beer, Natalie Scherrer, Juliane Schweizer, Mirjam Christ-Crain, Fabrizio Montecucco, Giovanni G. Camici, Mira Katan Kahles
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23211-y

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https://doi.org/10.1038/s41598-022-23211-y

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