Morphological and Proteomic Analyses Reveal that Unsaturated Guluronate Oligosaccharide Modulates Multiple Functional Pathways in Murine Macrophage RAW264.7 Cells

Morphological and Proteomic Analyses Reveal that Unsaturated Guluronate Oligosaccharide Modulates Multiple Functional Pathways in Murine Macrophage RAW264.7 Cells

Alginate is a natural polysaccharide extracted from various species of marine brown algae. Alginate-derived guluronate oligosaccharide (GOS) obtained by enzymatic depolymerization has various pharmacological functions. Previous studies have demonstrated that GOS can trigger the production of inducib...

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Bibliographic Details
Main Authors: Xu Xu, De-Cheng Bi, Chao Li, Wei-Shan Fang, Rui Zhou, Shui-Ming Li, Lian-Li Chi, Min Wan, Li-Ming Shen
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Marine Drugs
Subjects:
guluronate oligosaccharide
macrophage activation
nuclear factor-κB
anti-inflammation
antioxidant
cell morphology
Online Access:http://www.mdpi.com/1660-3397/13/4/1798

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http://www.mdpi.com/1660-3397/13/4/1798

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